Peptidomimetic Drug Screening Service for Cancer

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Peptidomimetic Drug Screening Service for Cancer

Constructing a large peptidomimetic library for phenotypic screening of various cancers is of great significance for the discovery of anticancer drugs. CD BioSciences provides construction and screening services of multiple peptidomimetic libraries for various cancer types, helping global customers find and research peptidomimetic drugs for cancer treatment.


Overview of Peptidomimetic as Anticancer Drugs

Overview of Peptidomimetics as Anticancer Drugs

Peptidomimetics are ideal components in cancer therapy because of their advantages in production, such as the possibility of automated chemical synthesis, and ease of modification. The unique advantage of peptidomimetics lies in biological interactions: they provide many possible interaction targets from cancer diagnosis to treatment.

The most influential applications of peptidomimetics in cancer therapy are in three fields: (1) simulating natural interactions between natural proteins or molecules to affect the viability of cancer, (2) targeted therapy or cancer diagnosis, and (3) delivering drugs across biological barriers. We will hopefully see the preclinical research and development of new candidate peptidomimetic drugs.

Advantages of Peptidomimetic Drugs

  • Excellent clinical safety and biocompatibility—Degradation products are amino acids-natural substances, which are nutrients or components in cells.
  • Can be chemically synthesized—Allows easy introduction of various modifications in a precisely controlled manner.
  • Smaller molecular weight—Conducive to penetrating various biofilm barriers.
  • Independent of the flow pump—Drug resistance is unlikely to occur.

Our Services

The design and synthesis of peptidomimetics undoubtedly have great potential in drug discovery. In CD BioSciences, we use our top PepDomTM platform to build a high-throughput peptidomimetic screening library with a capacity of 1012, providing peptidomimetic screening services for a variety of cancer types.

Our services include but are not limited to:

Cancer Type Common Cell Lines (Strains) Cancer Type Common Cell Lines (Strains)
Gastric Cancer MKN-45, SGC-7901, AGS, SNU-16 Lung Cancer A549, H460, H146, A-427, SPC-A1, H838
Liver Cancer HepG2, SMMC-7721, Hep3B, J5 Cervical Carcinoma HeLaHCC-94, MEG-01, MS751, HCE-1
Colon Cancer CT26, HCT-8 Oophoroma Caov-3, PA-1, Skov-3
Thyroid Cancer BC-PAP, TPC-1 Nasopharyngeal Carcinoma CNE-1; CNE-2, HNE1-3, HONE-1, SUNE-1
Head and Neck Cancer HN-5, UMSCC Esophageal Cancer TE-1, Eca109, EC109
Renal Carcinoma HRC-A498, 786-0, Caki-1, ACHN, OS-RC-2 Cholangiocarcinoma HUCCT1, RBE, HCCC-9810, CCLP-1
Bladder Cancer 5637, T24 Prostatic Cancer LNCaP, PC-3, DU145
Osteosarcoma 143B, SW1353, SaOS-2, U2OS, MG-63 Neuroma SK-N-AS, SH-SY5Y; BT325, SHG-44; U87, U373, H4; LN229
Breast Cancer ER Positive: MCF7, T-47D, ZR-75-1 Skin Cancer Melanoma:  B16F10, B16BL6, B78D4, SK-MEL-5, SK-MEL-28, SK-MEL-31
ER Negative: MDA-MB-231, SK-BR-3, MDA-MB-453, HCC1954 Non-melanoma:  SCC-13, HSQ-89, HSC-2, SCL-1; A431, TE-354-T
Lymphatic Carcinoma L-428, L1326; Raji, Daudi; WSU-FSCCL; SUDHL, Farage; TOLEDO, Karpas422; HuT-78; SNK-6 Pancreatic Cancer AsPC-1, BxPC-3, Capan-1, Capan-2, CFPAC-1, HPAC, HPAF-2, Hs-766T, MIA-Paca2, PANC-1, SU.86.86

Our Service Processes

Our Service Processes

Features of Our Services

Customizable

Customizable

Choose Diversity

Choose Diversity

Short Delivery Time

Short Delivery Time

Strict Efficacy Verification

Strict Efficacy Verification

CD BioSciences is committed to building a variety of large peptidomimetic libraries to screen drugs for a variety of cancer types. If you are interested in any aspect of peptidomimetic drug development for cancer treatment, please contact us for the best solution.

Reference

  1. Kurrikoff, K., Aphkhazava, D., & Langel, Ü. (2019). The future of peptides in cancer treatment. Current Opinion in Pharmacology, 47, 27–32.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.